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UPDATE: Acquisition of Moldyn Seen Boosting SBI s Databases

This story has been updated from a previous version.

NEW YORK, Dec 5 – The acquisition of Moldyn, a small subsidiary of Photon Research Associatiates, will be used to help strengthen Structural Bioinformatics’ protein structure databases, SBI’s CEO Edward Maggio said Tuesday.

“Moldyn, now SBI Moldyn, is a wholly owned subsidiary that focuses on developing advanced technologies based on the mathematics and physics that they’ve brought into the company [PRA] over the last seven years,” Maggio told GenomeWeb. “We are in discussions to commercialize their technologies as part of our database offering.”

Maggio said SBI acquired Moldyn in an all-stock transaction but he declined to offer details about the value of the deal.

Moldyn, a 10-person company based in Cambridge, Mass., was founded in 1993 to develop advanced algorithms for aero-space applications. Over the years, the company has begun applying its technology to life sciences and bioinformatics.

Moldyn’s MultiBody Order Dynamics technology, its only commercially available product, was initially developed to predict the motion of large satellites and space stations. Today MSI markets the technology as a way of computing how proteins change their shape. Maggio declined to offer any revenue figures for the MBOD technology.

The company’s Automated Structure Estimation and Refinement technology is designed to speed up the X-ray crystallography process, while its PeakDetect technology helps to solve the peak detection problem in MALDI-TOF mass spectrometry. SEQID uses multiple hypotheses tracking methods for de novo peptide sequence identification.

Maggio said that the company’s technologies would be used to beef up its ProMax and Variome databases. ProMax is a drug target database that contains thousands of proprietary target structures which are characterized by protein family. Variome offers a collection of modules for individual targets, including HIV protease and HIV reverse transcriptase.

The acquisition will also give SBI, a privately held company based in San Diego, more of a presence on the East Coast, said Maggio.

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