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UNLV's Biotech Center Survives Brief Power Outage During RT-PCR Runs

NEW YORK (GenomeWeb News) – The Biotechnology Center at the University of Nevada, Las Vegas, suffered a power outage lasting 36 minutes last month while it was performing real-time PCR runs, quantification, and capillary electrophoresis separation tasks, coordinator Walter Goldstein said this week.
Goldstein said a power surge caused by the outage “fried” some of the lab’s computers, but did not damage his lab instruments, among them sequencers made by Applied Biosystems, because the labs had auxiliary power-protection tools installed.
The UNLV lab has had a few outages, Goldstein sad, but added that because of the backup protection he has not suffered any instrument damage beyond computer hardware, or any loss of samples.

The Scan

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.