Back in 1997, biochemist Bruce Seligmann founded a combinatorial chemistry company called Systems Integration Drug Discovery. And since genomics was hot, he created a subsidiary as well: High Throughput Genomics, to apply the chemistry for high-throughput analysis of genomic samples.

As it turned out, combichem wasn’t that great a business to be in. So last year Seligmann sold the parent company and kept HTG, which alone had a market size “somewhere between $2 billion and $10 billion.”

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.