A Unique Snowflake

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They say that every snowflake is unique, that each of those millions of flakes has a slight difference. But when you widen your view, you don't see those small variations in shape anymore; you just see snow (and, perhaps, the need to find a shovel). As this issue's cover story says, cells also have slight differences — to their genomes, proteomes, and more. And, again, when you study a group of cells, those single-cell variations are lost.

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A new study finds that a placental protein linked with preeclampsia can be targeted by RNA silencing, according to the New Scientist.

A settlement is expected in a Duke University lawsuit hinging on using falsified data to win grants, Retraction Watch and Science report.

In PNAS this week: approach for analyzing the expression of endogenous retroviruses, circular RNAs that influence host-virus interactions, and more.

A phylogenetic analysis finds that the rare hemimastigotes form their own supra-kingdom, CBC reports.