On the Bright Side

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The debate over informed consent in early-phase clinical cancer trials rages on, says clinician Pauline Chen in a New York Times health column. Research on patients' motivations for signing up for such trials — which typically test only for toxicity and dosing, not therapeutic efficacy — indicate that despite explanations by researchers, they may never really understand the purpose of the trial.

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The Associated Press reports that the US government wasted $341,000 on travel by former Health and Human Services Secretary Tom Price.

Women who post YouTube science videos get more critical comments and more comments about their appearance than male video hosts, the New York Times reports.

The Wall Street Journal writes that participating in genetic research brings up the specter of past research ethics lapses for some African Americans.

In PLOS this week: sequences influencing yeast prion aggregation or degradation, dengue virus genetic variants affect transmission dynamics, and more.