Skip to main content

UK's Wellcome Trust Seeking to Fund New GWA Disease Studies

NEW YORK (GenomeWeb News) – The UK's Wellcome Trust is seeking independent researchers to conduct genome-wide association disease studies building on the GWA studies it began with the Wellcome Trust Case Control Consortium in 2005.
The Wellcome Trust said it aims to continue the “remarkable success” the WTCCC has had in screening entire genomes in large numbers of patients to find genetic variants that could play a role in diseases. The Wellcome Trust hopes that these variants could lead to new molecular targets for prevention, diagnosis, or treatment.
International research consortia are encouraged to apply for the funding, provided they are led by an investigator based in the UK or Republic of Ireland.
The WTCCC awarded £30 million (around $46 million) in January of this year to fund 27 new studies that extended the range of diseases or traits it was investigating.
Researchers may apply for awards either in collaboration with the WTCCC or independently. All will have access to validated genotypes from 600 common controls from the UK that were typed using Illumina and Affymetrix technology. Those collaborating with the WTCCC will have access to its centralized DNA handling, quality control, genotyping, and data analysis resources.
Wellcome Trust will assess the genotyping strategy researchers plan to use and the platforms they propose using, and it wants to know how the material will be analyzed and who will conduct the analysis. It also wants to know the bioinformatics infrastructure and expertise that researchers have available for data handling.
More information about the Wellcome Trust’s call for proposals is available here.

The Scan

UK Funds to Stay Ahead of Variants

The UK has announced a further £29.3 million to stay on top of SARS-CoV-2 variants, the Guardian reports.

Push for Access

In a letter, researchers in India seek easier access to COVID-19 data, Science reports.

Not as Cold

Late-stage trial results are expected soon for an RNA-based vaccine that could help meet global demand as it does not require very cold storage, the New York Times writes.

Genome Research Papers on Microbes' Effects on Host Transfer RNA, Honeybee Evolution, Single-Cell Histones

In Genome Research this week: influence of microbes on transfer RNA patterns, evolutionary relationships of honeybees, and more.