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UK Team Sequences Genome of Potato Rot Bacterium

NEW YORK, July 20 (GenomeWeb News) - A team of researchers led by the Wellcome Trust Sanger Institute has sequenced the genome of Erwinia carotovora (Eca) subsp. atroseptica, a member of the Enterobacteriaceae bacterial family that causes soft rot and blackleg in potatoes.


The team published its analysis of the five million-bp genome for Eca strain SCRI1043 in today's online version of the Proceedings of the National Academy of Sciences.


Analysis of the organism's genome, sequenced to 10.2-fold coverage, revealed 4,491 predicted coding sequences. Around 33 percent of these putative genes are not shared with sequenced enterobacterial human pathogens, such as Salmonella, Yersinia, and Shigella, and may be involved in pathogenicity and metabolism, according to the researchers.

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.