NEW YORK, June 24 (GenomeWeb News) - A group led by researchers at the Wellcome Trust Sanger Institute in Cambridge, UK, has mapped the genome of two disease-causing strains of Staphylococcus aureus.
The research was published in the June 22 online (before-print) version of PNAS. According to the paper's abstract, the researchers sequenced the approximately 2.8-Mbp genomes of two S. aureus strains - one methicillin-resistant and one methicllin-susceptible - isolated from distinct clinical settings. The scientists then compared the genomes to identify regions affecting virulence and drug resistance.
S. aureus is an important nosocomial and community-acquired pathogen, and its genetic plasticity has produced several virulent and drug-resistant strains, according to the paper's abstract, which can be found here.