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U of Aberdeen Researcher Lands $200K to Study Protein Biomarkers for Colon Cancer

NEW YORK (GenomeWeb News) – A scientist at Scotland’s University of Aberdeen will use a £105,000 ($211,000) grant from the Association for International Cancer Research, a Scotland-based non-profit, to study proteins that could be used as diagnostics and therapeutics for early-stage colon cancer, the AICR said Wednesday. 
Graeme Murray at Aberdeen’s Department of Pathology said his team will use a “large collection” of colon cancer samples that include information about the stage of cancer, “and we will look for characteristic changes in the proteins of each to find out if we can use this information and knowledge to see if it can be used as a new way to diagnose the stages of this killer cancer.”
Although the outlook for patients with this type of cancer has improved significantly over the last 20 years, currently only about half of colon cancer patients survive five years after diagnosis, said AICR Scientific Officer, Mark Matfield.

The Scan

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.

EHR Quality Improvement Study Detects Demographic-Related Deficiencies in Cancer Family History Data

In a retrospective analysis in JAMA Network Open, researchers find that sex, ethnicity, language, and other features coincide with the quality of cancer family history information in a patient's record.

Inflammatory Bowel Disease Linked to Gut Microbiome Community Structure Gradient in Meta-Analysis

Bringing together data from prior studies, researchers in Genome Biology track down microbial taxa and a population structure gradient with ties to ulcerative colitis or Crohn's disease.

Ancient Greek Army Ancestry Highlights Mercenary Role in Historical Migrations

By profiling genomic patterns in 5th century samples from in and around Himera, researchers saw diverse ancestry in Greek army representatives in the region, as they report in PNAS.