Skip to main content
Premium Trial:

Request an Annual Quote

Transgenomic sells Wave System to Genzyme

NEW YORK, April 23 – Transgenomic has sold its Wave genetic analysis system to biotechnology giant Genzyme, the companies said Monday.

Genzyme will use the system in its research on genetic mutations that cause or are associated with hereditary diseases such as lysosomal storage disorders and some cancers. 

"The ongoing challenge for human genome research is to understand the relationship between genetic mutations and diseases such as cancer,” said Transgenomic Chief Executive Officer, Collin D'Silva, in a statement. “The Wave System has been widely recognized as one of the fastest, most sensitive and cost-effective tools for genetic analysis."

The Wave System is designed to identify DNA mutations using micro-bead technology. The product packs micro-beads, each of which has a proprietary surface chemistry that interacts with DNA molecules, into a DNA separation column. The product than uses liquid reagents to separate out the molecules. The analysis is performed using the company’s bioinformatics Wavemaker software

D’Silva said that Transgenomic, of Omaha, Neb., has placed the Wave system in over 500 medical research institutions and biotechnology companies.

The Scan

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.

SpliceVault Portal Provides Look at RNA Splicing Changes Linked to Genetic Variants

The portal, described in Nature Genetics, houses variant-related messenger RNA splicing insights drawn from RNA sequencing data in nearly 335,700 samples — a set known as the 300K-RNA resource.

Automated Sequencing Pipeline Appears to Allow Rapid SARS-CoV-2 Lineage Detection in Nevada Study

Researchers in the Journal of Molecular Diagnostics describe and assess a Clear Labs Dx automated workflow, sequencing, and bioinformatic analysis method for quickly identifying SARS-CoV-2 lineages.

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.