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Tomorrow’s PIs: Class of 2006


Joshua Akey won two grants to study human genetic diversity.

Bradley Bernstein won an NHGRI ENCODE grant to sequence chromatin regulatory elements.

Mya Breitbart uses metagenomic analyses to study the viromes of oceans.

Atul Butte won two grants, one of which is to help create a diabetes knowledge base.

Steven Cannon published a paper analyzing a BAC library of the white clover.

Anne Carpenter now directs the Broad Institute's Imaging Platform.

Joshua Coon won a grant for large peptide and whole protein characterization.

Adolfo Ferrando received a grant from NCI to study Notch1-induced T-cell leukemogenesis.

John Fondon is researching the genetic influence on morphologic evolution in dogs.

Frank Grutzner is now an ARC postdoctoral fellow at Australia National University.

Taekjip Ha published a paper describing a new method for unwinding DNA.

Michael Hemann won an NCI grant for a project using RNAi in vivo.

Manolis Kellis won an NHGRI grant to find novel regulatory motifs in the human genome.

Holger Kirsten uses single-base extension technology for clinical genotyping.

Jens Kurreck published a method for using RNAi to study viral infection of cardiac cells.

Martin Rossel Larsen is working on identifying protein glycosylation bio-markers.

Michael MacCoss won a grant from NCI to analyze protein dynamics in C. elegans.

Elliott Margulies was a co-author on the paper for the ENCODE pilot project, published in June 2007.

Alexey Nesvizhskii got an NCI grant to do computational analysis of proteomic datasets.

Tera Newman studies structural variation in the human genome.

Babak Parviz was one of Technology Review’s 2007 Young Innovators Under 35.

Nathan Price is now an assistant professor at the University of Illinois, Urbana.

Pablo Rabinowicz is working on research of epigenetic variation in Arabidopsis thaliana.

Ben Raphael was part of the Sorcerer II ocean sampling expedition for proteins.

Heidi Rehm published a paper that looks at the probable genetic causes of   hearing loss.

Marylyn Ritchie launched ESE, exhaustive SNP exploration, a data analysis software.

Andy Sharp published work on disease-related genomic rearrangements.

Adam Siepel was a co-author on the ENCODE pilot project, published in June 2007.

Kimberly Stegmaier won an NCI grant to investigate leukemia differentiation.

Hiroki Ueda studies the mammalian circadian clock from a systems perspective.


The Scan

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.

Coronary Artery Disease Risk Loci, Candidate Genes Identified in GWAS Meta-Analysis

A GWAS in Nature Genetics of nearly 1.4 million coronary artery disease cases and controls focused in on more than 200 candidate causal genes, including the cell motility-related myosin gene MYO9B.

Multiple Sclerosis Contributors Found in Proteome-Wide Association Study

With a combination of genome-wide association and brain proteome data, researchers in the Annals of Clinical and Translational Neurology tracked down dozens of potential multiple sclerosis risk proteins.

Quality Improvement Study Compares Molecular Tumor Boards, Central Consensus Recommendations

With 50 simulated cancer cases, researchers in JAMA Network Open compared molecular tumor board recommendations with central consensus plans at a dozen centers in Japan.