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Tips for Targeted Cancer Treatment


Personalized medicine is gaining ground in the clinic, but when it comes to cancer treatment, it has both advantages and disadvantages, says Scientific American guest blogger Karen Ventii. A personalized approach to cancer can result in better treatment for the patient and a reduced cost for care, but it can also increase cancer cells' potential to develop resistance to treatment. To get around this, Ventti says, it may be necessary to use targeted therapies in combination with either other targeted therapies or more conventional ones. "Cancer is a complex genetic disease and as more is learned about the genetic mechanics of cancer growth, the hope is that this knowledge will be leveraged to identify new molecular diagnostics and provide new strategies for tailoring therapies to fit the needs of each cancer patient's unique biology," she adds.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.