Skip to main content
Premium Trial:

Request an Annual Quote

TIGM Concludes First Round of OmniBank Mouse Knockout Library Installation

NEW YORK, June 14 (GenomeWeb News) - The Texas Institute for Genomic Medicine said today that it has completed the first installation of Lexicon Genetics' OmniBank II library of mouse gene knockouts at its facilities in Houston and College Station.


TIGM also said that it will begin constructing a new building next week in College Station to house the library. Lexicon announced the deal to create the library, worth $35 million, in July 2005.


The initial library installation contains more than 90,000 clones, each representing an embryonic stem cell line in which a single gene has been knocked out, TIGM said.


The next installation is expected to be completed in December. When the entire library is completed, in 2008, the it is expected to house 350,000 mouse embryonic stem cell clones, according to the institute.

The Scan

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.

Study Explores Animated Digital Message Approach to Communicate Genetic Test Results to Family Members

In the Journal of Genetic Counseling, the approach showed promise in participants presented with a hypothetical scenario related to a familial hereditary breast and ovarian cancer syndrome diagnosis.

Computational Tool Predicts Mammalian Messenger RNA Degradation Rates

A tool called Saluki, trained with mouse and human messenger RNA data, appears to improve mRNA half-life predictions by taking RNA and genetic features into account, a Genome Biology paper reports.

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.