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Third Wave, Labcorp To Co-Develop Companion Dx for Arca Discovery's Heart Failure Drug

NEW YORK (GenomeWeb News) - Third Wave Technologies said today that it will collaborate with Laboratory Corporation of America to develop a diagnostic that may be used in conjunction with a heart failure drug that is being developed by Arca Discovery. 
 
The diagnostic is intended to help physicians determine use of the drug bucindolol, a beta blocker that Third Wave said could be "the first genetically targeted cardiovascular drug."
 
The test will be developed in tandem with the drug's approval process, the company added.
 
Bucindolol has shown "extensive" efficacy and safety in Phase III trials, Third Wave said, noting that Arca plans to use genetic data to target patients most likely to respond to the drug when it seeks FDA approval in 2008.
 
Labcorp acquired the rights to develop and commercialize the companion diagnostic for the Arca drug in February.
 
Financial terms of the agreement were not released.

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