Skip to main content
Premium Trial:

Request an Annual Quote

TGen and Kronos to Study 570K SNPs in Alzheimer s Research

NEW YORK, Feb. 24 (GenomeWeb News) - The Translational Genomics Research Institute and Kronos Science Laboratories will cooperate in an Alzheimer's research study, the institute said yesterday.

 

The 18-month study is expected to cost approximately $6 million and will be jointly funded by TGen and Kronos, a subsidiary of Kronos Optimal Health. Both are located in Phoenix.

 

In the study, researchers will examine some 570,000 SNPs from deceased individuals who were confirmed to have Alzheimer's disease at autopsy, and another 1,000 dead who were confirmed to be free of the disease at autopsy. DNA samples will be obtained from brain banks in the USand Europe.

 

Kronos will have an exclusive worldwide license to all intellectual property that results from the research, and will look to develop a diagnostic for genetic predisposition.

The Scan

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.

Coronary Artery Disease Risk Loci, Candidate Genes Identified in GWAS Meta-Analysis

A GWAS in Nature Genetics of nearly 1.4 million coronary artery disease cases and controls focused in on more than 200 candidate causal genes, including the cell motility-related myosin gene MYO9B.

Multiple Sclerosis Contributors Found in Proteome-Wide Association Study

With a combination of genome-wide association and brain proteome data, researchers in the Annals of Clinical and Translational Neurology tracked down dozens of potential multiple sclerosis risk proteins.

Quality Improvement Study Compares Molecular Tumor Boards, Central Consensus Recommendations

With 50 simulated cancer cases, researchers in JAMA Network Open compared molecular tumor board recommendations with central consensus plans at a dozen centers in Japan.