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TCGA Taps Rubicon for Cancer Sample Amplification

NEW YORK (GenomeWeb News) – Rubicon Genomics will amplify and standardize DNA samples from cancer patients for the Cancer Genome Atlas, the Ann Arbor, Mich.-based company said today.
 
Under an agreement with SAIC-Frederick, Rubicon will use its GenomePlex whole-genome amplification technology on more than 3,000 blood and tissue samples. The DNA libraries will be deposited in the International Genomics Consortium’s Biospecimen Research Core, where they will be shared among international researchers taking part in the TCGA project.
 
Rubicon’s VP of commercial development, John Langmore, said in a statement that IGC collaborators showed “that pre-amplification of patient DNA can increase the sensitivity, reproducibility and robustness of analysis of patient samples using major analytical instruments."
 
Financial terms of the agreement were not released.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.