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T Cell Generals Lead a Cancer-Killing Army


Researchers at the National Cancer Institute have identified a new class of T cells, which they say behaves like stem cells do. According to an NIH press release, these T cells prolong the immune attack against cancer cells by continuously producing a supply of "killer T cells" while constantly regenerating themselves. In their study, published recently in Nature Medicine, the researchers say that these cells comprise 1 percent to 2 percent of T cells in most of the donor blood they studied. But because they are so powerful, the press release adds, they could be used in T-cell therapies and could, in theory, integrate with a person's immune system for a long period of time, or even permanently, to continually fight any tumor cells that may develop.

The Scan

Review of Approval Process

Stat News reports the Department for Health and Human Services' Office of the Inspector General is to investigate FDA's approval of Biogen's Alzheimer's disease drug.

Not Quite Right

A new analysis has found hundreds of studies with incorrect nucleotide sequences reported in their methods, according to Nature News.

CRISPR and mRNA Together

Time magazine reports on the use of mRNA to deliver CRISPR machinery.

Nature Papers Present Smartphone Platform for DNA Diagnosis of Malaria, Mouse Lines for Epigenomic Editing

In Nature this week: a low-cost tool to detect infectious diseases like malaria, and more.