Not surprisingly, systems biology has made its way over to the National Cancer Institute. Last fall NCI announced that it would divvy up $14.9 million over five years among nine Integrative Cancer Biology Program centers to fund systems-wide approaches to cancer research. The focus, according to NCI, is on building predictive models of cancer.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.