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Study Provides Clue to Heart Disease, Stroke Genetic Risk Factors

NEW YORK, Dec. 23 (GenomeWeb News) - Thanks to a new genomics study, researchers may have finally found a firm link between certain genetic markers that appear to contribute to a higher risk of heart disease, diabetes, or stroke, according to a paper published this month in The Journal of Clinical Endocrinology and Metabolism, a journal published by The Endocrine Society. Such a link, while suspected, has never been proven.

Claude Bouchard and fellow researchers at the Pennington Biomedical Research Center in Baton Rouge, La., used more than 500 markers to perform whole-genome scans in a family study. Focusing on genomic regions that might have an influence on metabolic syndrome, the group found that the segments that were determined to be the most important were ones that have in the past been linked to risk factors for diabetes and cardiovascular disease.

"These findings bring us closer to discovering the actual genes that are responsible for metabolic syndrome, which puts patients at risk for so many serious health problems," Bouchard said in a statement. "This information could someday help doctors assess whether specific patients are at risk for developing the metabolic syndrome based on their genes."

According to the Centers for Disease Control and Prevention, 47 million Americans are affected by metabolic sydrome.


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