Skip to main content
Premium Trial:

Request an Annual Quote

Structural Genomix in $11M Deal with Cystic Fibrosis Foundation

NEW YORK, Feb 8 - Structural Genomix said Thursday it reached an agreement with the Cystic Fibrosis Foundation to determine the structure of a protein, cystic fibrosis transmembrane regulator, which is involved in causing cystic fibrosis.

" CF scientists have attempted to determine the structure of the CFTR protein, but without a lot of success. The CF Foundation thinks that Structural Genomix will bring new cutting edge technologies to the problem, and hopefully accomplish this difficult task," Robert Beall, CEO of the Cystic Fibrosis Foundation, said in a statement.

Under the terms of the five-year deal, the Cystic Fibrosis Foundation will give $11 million to Structural Genomix in research funding and will pay additional milestone and royalty payments.

Structural Genomix, which employs x-ray crystallography to determine protein structures, will study sequence variations in the CFTR gene across species to determine the x-ray structure of the protein. A defective gene that codes for the CFTR protein causes the development of a thick mucus that damages airways and the digestive tract and leads to a host of infectious diseases.

The company said that no 3-D structure of CFTR currently exists.

Structural Genomix of San Diego and the Cystic Fibrosis Foundation hope that by understanding the structure of CFTR, drug makers will be able to develop new compounds and therapies for cystic fibrosis.

The Scan

More Boosters for US

Following US Food and Drug Administration authorization, the Centers for Disease Control and Prevention has endorsed booster doses of the Moderna and Johnson & Johnson SARS-CoV-2 vaccines, the Washington Post writes.

From a Pig

A genetically modified pig kidney was transplanted into a human without triggering an immune response, Reuters reports.

For Privacy's Sake

Wired reports that more US states are passing genetic privacy laws.

Science Paper on How Poaching Drove Evolution in African Elephants

In Science this week: poaching has led to the rapid evolution of tuskless African elephants.