One year ago this month, Genome Technology’s cover story attacked cancer from a handful of systems biology standpoints, from bioinformatics to RNAi. We spoke with Colin Hill, co-founder of Gene Network Sciences, who introduced us to his company’s approaches to modeling the mechanisms of cancer drugs. These days, the biosimulation firm’s technology is being used to classify patient subgroups and identify biomarkers in clinical settings thanks to a partnership with the Mary Crowley Medical Research Center.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.