To Stop the Spread

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A team led by researchers at Harvard Medical School says that molecular investigations into circulating tumor cells could facilitate the identification of candidate therapeutic targets to stop the spread of cancer. In a paper published online in advance in Nature this week, Harvard's Daniel Haber and his colleagues report on their use of single-molecule RNA-seq to identify candidate genes enriched in circulating tumor cells from an endogenous mouse pancreatic cancer model.

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In PNAS this week: DNA methylation profiles of tumor tissue, gene dynamics in prokaryotes, and more.