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Starting a 'Revolution'


Cancer research has benefitted greatly from the sequencing of the human genome, Big Think says. Initiatives like the Cancer Genome Atlas, which systematically maps key genomic changes in various types and subtypes of cancer, are part of the information boom the cancer research field has experienced in recent years. At a panel discussion of cancer researchers organized by Big Think, National Cancer Institute Director Harold Varmus said the full picture of how genetics and genomics have changed how we think of cancer is "really very dramatic and quite wonderful."

The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.