NEW YORK (GenomeWeb News) – The synthetic biology company Sloning will use its DNA engineering platform in a joint gene mutant library project with researchers at Stanford University, the Munich-based company said today.
Sloning said that it will use its Slonomics platform to synthesize a gene mutant library where certain codons are introduced in a statistically expected and controlled ratio at preselected positions within a given DNA sequence.
The reserachers at Stanford, led by Roger Kornberg, will run in vivo screens based on Sloning’s gene mutant library to identify relevant mutants of a S. cerevesiae RNA polymerase II. Kornberg said the “mutant library will allow us to dissect and better understand the transcription mechanism."
Sloning uses its platform to synthesize customized mutant libraries for its customers in biopharmaceutical, agribiotech, industrial biotech, and food industries.