Skip to main content
Premium Trial:

Request an Annual Quote

Spectral Genomics Unveils Human BAC Arrays

NEW YORK, March 27 – Spectral Genomics of Houston launched Tuesday its SpectralChip Human BAC Arrays.

The company said its Human SpectralChip Microarray Kit comes with two arrays with 1,003 non-overlapping BAC clones from the RPCI BAC library, which are spotted in duplicate. The kit also includes reagents and solutions for labeling and hybridization. The BACs span the genome at approximately 3mb intervals, thus only enabling the detection of aberrations greater than 3mb.

The company indicated that its human arrays could be particularly useful as a diagnostic tool for genotyping tumors since the arrays could generate a genome wide molecular profile and quantify chromosomal imbalances on a single chip. Chromosomal imbalances characterize most solid tumors.

The company said that its technology differs from other microarray technologies because it does not require the substrate’s surface to be modified through chemical processes that involve poly-L-lysine or silane. Instead, Spectral Genomics uses a proprietary chemical coupling of large DNA fragments to untreated surfaces.

“DNA glass microarrays produced by this method have several major advantages over traditional glass microarrays," Shishir Shah, president of Spectral Genomics, said in a statement.

Shah was not immediately available for comment.

Last week Spectral Genomics introduced a similar mouse BAC array.

The Scan

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.

EHR Quality Improvement Study Detects Demographic-Related Deficiencies in Cancer Family History Data

In a retrospective analysis in JAMA Network Open, researchers find that sex, ethnicity, language, and other features coincide with the quality of cancer family history information in a patient's record.

Inflammatory Bowel Disease Linked to Gut Microbiome Community Structure Gradient in Meta-Analysis

Bringing together data from prior studies, researchers in Genome Biology track down microbial taxa and a population structure gradient with ties to ulcerative colitis or Crohn's disease.

Ancient Greek Army Ancestry Highlights Mercenary Role in Historical Migrations

By profiling genomic patterns in 5th century samples from in and around Himera, researchers saw diverse ancestry in Greek army representatives in the region, as they report in PNAS.