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Solexa Uses its SBS Technology to Sequence 5K-Base Virus

NEW YORK, March 10 (GenomeWeb News) - Solexa today reported that it has sequenced the 5,000-base genome of the Phi-X 174 virus using its sequencing-by-synthesis technology.

 

The sequencing effort using the developmental technology covered the entire genome of the virus at an accuracy rate of 99.93 percent, said Solexa. The process delivered more than 3 million bases from a single sample preparation and detected at least three mutations subsequently confirmed by conventional DNA sequencing techniques, the company said.

 

Solexa and Lynx Therapeutics earlier this month completed a merger first announced last September.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.