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Solexa Uses its SBS Technology to Sequence 5K-Base Virus

NEW YORK, March 10 (GenomeWeb News) - Solexa today reported that it has sequenced the 5,000-base genome of the Phi-X 174 virus using its sequencing-by-synthesis technology.

 

The sequencing effort using the developmental technology covered the entire genome of the virus at an accuracy rate of 99.93 percent, said Solexa. The process delivered more than 3 million bases from a single sample preparation and detected at least three mutations subsequently confirmed by conventional DNA sequencing techniques, the company said.

 

Solexa and Lynx Therapeutics earlier this month completed a merger first announced last September.

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.