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SNPTECH REPORTER SUBSCRIBERS: A Lighter 800-Pound Gorilla, Applied Biosystems Takes Aim at Genotyping

Applied Biosystems has crept onto the genotyping scene with a three-pillar strategy designed to take aim at market leaders Sequenom and Illumina. But a weak tool market has wounded the sequencing giant, even forcing it to issue a terse warning to investors that deteriorating business will hamstring top-line growth for the remainder of this fiscal year. How will ABI s strategy fare? Subscribe. (https://www.snptech.com/subscribe.htmtarget=_blank)

The Scan

Octopus Brain Complexity Linked to MicroRNA Expansions

Investigators saw microRNA gene expansions coinciding with complex brains when they analyzed certain cephalopod transcriptomes, as they report in Science Advances.

Study Tracks Outcomes in Children Born to Zika Virus-Infected Mothers

By following pregnancy outcomes for women with RT-PCR-confirmed Zika virus infections, researchers saw in Lancet Regional Health congenital abnormalities in roughly one-third of live-born children.

Team Presents Benchmark Study of RNA Classification Tools

With more than 135 transcriptomic datasets, researchers tested two dozen coding and non-coding RNA classification tools, establishing a set of potentially misclassified transcripts, as they report in Nucleic Acids Research.

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.