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In Silico: May 1, 2002


www.GenomeWeb.COM Daily


And a Bag of Chips


An industry study predicts that sales of protein chips will exceed $700 million in 2006, a 10-fold increase from the $76 million in sales the industry recorded one year ago. “With at least 25 companies either selling protein biochips today or preparing to enter the market within the next two years, sales … are poised for enormous growth,” according to BioInsights, which conducted the study.


Find “Protein Chip Market Poised to Exceed $700M by 2006” by searching: protein chip


On the Verge?


Paracel’s future as a Celera Genomics subsidiary is unclear. As Celera slips into new drug discovery duds, it has to decide what to do with the upstream technologies and businesses that made it a genomics powerhouse. It sold AgGen and is weighing its options for its online business.


Find “Paracel’s Future Uncertain as Celera Sheds Tool-Shop Skin” by searching: Paracel


Hail to the Cash


If there’s one thing that publicly traded genomics companies may count on After Enron it is that cash is the new king. And considering that nearly all genomic tool and tech shops burn more cash than they earn, the new standard presents novel challenges.


Find “For Public Genomics Firms, Cash is King in Post-Enron Twilight” by searching: Enron


www.BIOarraynews.COM WEEKLY


Diagnostic Diagnosis


“There are going to be three or four major platforms for diagnostics,” said Jorge Leon, vice president of applied genomics at Quest Diagnostics. “One of them is going to be [DNA] arrays,” he said. The others will include immunoassays, traditional ELISAs and antibody arrays, as well as fluorescent in situ hybridization and protein mass spectrometry.


Find “DNA Microarrays Enter the Realm of Clinical Diagnostics, but Their Future Role Is Unclear” by searching: diagnostics




Wheelin’ and Dealin’


Cray and Compaq have recently established a foothold in Singapore’s emerging bioinformatics efforts via deals with the country’s leading academic institutions — a supercomputer at the National University of Singapore and bioinformatics software at Nanyang Technological University.


Find “Compaq and Cray Stake Their Claims in Singapore’s Fertile Bioinformatics Territory” by searching: Singapore




TOF Choices


Scientists in the field speak with anticipation of the days when high-end instruments such as the MALDI-TOF/TOF will prove themselves cost-effective. But beneath that swell of expectation lies an undercurrent: for proteomics experiments involving the analysis of complex mixtures of peptides, has the cost of Q-TOF technology dipped to the point where ion traps are no longer necessary?


Find “Mass Spectrometrists Debate: Q-TOFs or Ion Traps for Analyzing Complex Peptide Mixtures” by searching: Q-TOF


The Scan

Push Toward Approval

The Wall Street Journal reports the US Food and Drug Administration is under pressure to grant full approval to SARS-CoV-2 vaccines.

Deer Exposure

About 40 percent of deer in a handful of US states carry antibodies to SARS-CoV-2, according to Nature News.

Millions But Not Enough

NPR reports the US is set to send 110 million SARS-CoV-2 vaccine doses abroad, but that billions are needed.

PNAS Papers on CRISPR-Edited Cancer Models, Multiple Sclerosis Neuroinflammation, Parasitic Wasps

In PNAS this week: gene-editing approach for developing cancer models, role of extracellular proteins in multiple sclerosis, and more.