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In Silico: Sep 1, 2001


GenomeWeb.COM Daily


“Obviously, you can fight this to the death, or you can agree to settle it.”

— Nanogen CFO Gerard Wills on the Nanogen/Motorola settlement over electricity-based DNA detection technology, in which Nanogen agreed to pay $5 million.

Find “Nanogen Reaches Settlement with Motorola in Patent Dispute” by searching: Nanogen

Proteins à Paris

Oxford Glycosciences and Hybrigenics have entered into a collaboration to study OGS’ protein drug targets. Hybrigenics will use modified yeast two-hybrid and similar cellular screening technologies to attempt to validate OGS’ proteins as involved in disease-related pathways.

Find “Hybrigenics to Study Interactions of OGS’ Protein Targets” by searching: OGS


So Long, Farewell

GenomicFX, an animal genomics company based in Austin, Texas, will close its doors in August, GenomeWeb learned. GenomicFX originally said it would create animal blood tests to help livestock breeders select animals as well as develop an identification tool to verify breed or origin.

Find “GenomicFX to Close Its Doors in August” by searching: GenomicFX


Speedy Smith-Waterman

Compaq and Edinburgh Biocomputing Systems said they had successfully achieved one billion comparisons per second running the Smith-Waterman algorithm on a single 1 GHz Alpha processor using EBS’ MPSRCH sequence analysis software. Compaq will begin shipping the 1 GHz Alphas in the fall.

Find “Compaq and EBS Break Billion Comparison-per-Second Barrier in 1 GHz Alpha Demo” by searching: EBS


Celera Sequel

While Celera Genomics and ABI focus on drug discovery and tools, Celera Diagnostics will begin building an industrial-scale genotyping facility in Alameda, Calif., to identify gene and protein markers for disease. It has not yet decided which specific disease to target, but it hopes to break into molecular, protein chemistry, and immunochemistry diagnostics.

Find “Celera Diagnostics Begins to Find Its Place Within Applera” by searching: Applera



Bracing for a Boycott

Michael Eisen, ringleader of a looming 25,000-scientist boycott of the scientific journals, compared the current publishing process to a midwife who delivers a baby and then charges its parents to visit it.

Find “Public Library of Science Issues Ultimatum; Prepares for Journal Boycott, Self Publication” by searching: boycott


Back to School

BioInform publishes a comprehensive list of US universities offering bioinformatics BS, MS, and PhD programs with data on graduate job placement and administrators’ contact information.

Find “Bioinformatics Gains Foothold on US Campuses: 30 Universities Now Offer Degrees” by searching: campuses



DIY Special

Need to order your own custom-designed oligonucleotide array at 3 a.m.? Now Affymetrix customers can do just that, with a new CustomExpress program and the company’s NetAffx website. Turnaround time for these made-to-order arrays, which cost $250 each in addition to a design fee, is currently four weeks. “We don’t think people expected they could do this with photolithography,” says Affymetrix president Sue Seigel.

Find: “New Affymetrix Offering Heats up Custom Array Market: Luminex to Launch Custom Bead Array,” by searching: Affymetrix


The Scan

Boosters Chasing Variants

The New York Times reports that an FDA advisory panel is to weigh updated booster vaccines for COVID-19.

Not Yet

The World Health Organization says monkeypox is not yet a global emergency, the Washington Post reports.

More Proposed for Federal Research

Science reports that US House of Representatives panels are seeking to increase federal research funding.

PLOS Papers on Breast Cancer Metastasis, Left-Sided Cardiac Defects, SARS-CoV-2 Monitoring

In PLOS this week: link between breast cancer metastasis and CLIC4, sequencing analysis of left-sided cardiac defects, and more.