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Sigma-Aldrich Pays Sangamo $1M ZFN Milestone

NEW YORK (GenomeWeb News) — Sigma-Aldrich has paid Sangamo BioSciences a $1 million milestone as part of a deal for Sangamo to develop zinc finger nuclease reagents for the research market, Sangamo said this week.

The payment was a production milestone under an agreement the companies made in July 2007.

ZFNs can be designed to target any gene in any organism, Sangamo said, and can be used to rapidly make precise changes to a cell's characteristics

David Smoller, president of Sigma-Aldrich's Research Biotech business, said in a statement that the reagent platform, which it will market, will provide researchers with "the ability to precisely manipulate the genome of living cells, resulting in cell lines or whole organisms with defined gene deletions, insertions, or corrections."

The Scan

Shape of Them All

According to BBC News, researchers have developed a protein structure database that includes much of the human proteome.

For Flu and More

The Wall Street Journal reports that several vaccine developers are working on mRNA-based vaccines for influenza.

To Boost Women

China's Ministry of Science and Technology aims to boost the number of female researchers through a new policy, reports the South China Morning Post.

Science Papers Describe Approach to Predict Chemotherapeutic Response, Role of Transcriptional Noise

In Science this week: neural network to predict chemotherapeutic response in cancer patients, and more.