Skip to main content
Premium Trial:

Request an Annual Quote

Sigma-Aldrich Allies With MIT s RNAi Consortium; Will Help Develop, Distribute Reagents

NEW YORK, March 16 (GenomeWeb News) - Sigma-Aldrich has become a "scientific collaborator" and distribution partner to MIT's RNAi Consortium, bringing to four the number of TRC's corporate partners, the company said today.


The TRC's three-year goal is "to create a comprehensive library of RNA Interference reagents designed to reduce expression of specific human and mouse genes, thereby enabling scientists to elucidate the function of the targeted gene," according to a statement.


To that end, Sigma-Aldrich will help the consortium develop and distribute clones, purified DNA, and viral stocks from the group's RNAi libraries to researchers worldwide, the company said.


Based at The Broad Institute, the consortium comprises seven research institutions, including Massachusetts General Hospital, Harvard Medical School, Dana-Farber Cancer Institute, The Broad Institute, Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, and Academia Sinica. It is also home to four companies, including Bristol-Myers Squibb, Eli Lilly, Novartis, and now Sigma.


Financial terms of Sigma's participation were not disclosed.

The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.