Bruce Roe, director of University of Oklahoma’s Advanced Center for Genome Technology, has an almost religious devotion to Chromosome 22. As part of the Human Genome Project, his center led sequencing of that chromosome, which achieved fame as the first to be completed back in December 1999. As this year’s grant submission deadline came up in March, Roe and his colleagues busily prepared requests to do comparative and functional genomics with Chromosome 22.

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