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Sequencing Grants


Following are the recipients of NHGRI’s latest sequencing technology RFAs, including PI and affiliation, project name, and funding amount and duration.


“$100,000 Genome” Near-term Grant Awardees:

Steven Benner, University of Florida

Polymerases for Sequencing by Synthesis

$800,000, three years

Gina Costa, Agencourt Bioscience

Bead-based Polony Sequencing

$5.4 million, three years

Stevan Jovanovich, Microchip Biotechnologies

Microbead INtegrated DNA Sequencer System

$6.1 million, three years

Jingyue Ju, Columbia University

An Integrated System for DNA Sequencing by Synthesis

$1.8 million, three years

Kenton Lohman, 454 Life Sciences

Massively Parallel High-Throughput, Low-Cost Sequencing

$2 million, two years

Marcel Margulies, 454 Life Sciences

454 Life Sciences Massively Parallel System DNA Sequencing

$5 million, three years

Amit Meller, Harvard University

Ultra-fast Nanopore Readout Platform for Designed DNAs

$600,000, two years

Michael Metzker, Baylor College of Medicine

Ultrafast SBS Method for Large-Scale Human Resequencing

$2 million, three years

Stephen Quake, Stanford University

High-Throughput, Single-Molecule DNA Sequencing

$1.8 million, three years

Mostafa Ronaghi, Stanford University

Pyrosequencing Array for DNA Sequencing

$1.8 million, three years

John Williams, LI-COR

Single-Molecule DNA Sequencing Using Charge-Switch dNTPs

$2.5 million, three years

Peter Williams, Arizona State University

Multiplexed Reactive Sequencing of DNA

$1.7 million, three years


“$1,000 Genome” Long-term Grant Awardees:

Steven Benner, University of Florida

DNA Sequencing Using Nanopores

$800,000, three years

Scott Collins, University of Maine

High-speed Nanopore Gene Sequencing

$850,000, two years

Ronald Davis, Stanford University

Single Molecule Nucleic Acid Detection with Nanopipettes

$450,000, two years

James Weifu Lee, Oak Ridge National Laboratory

Computational Research & Development for Rapid Sequencing Nanotechnology

Experimental Research & Development for Rapid Sequencing Nanotechnology

Two grants: $700,000 and $750,000, each for three years

Stuart Lindsay, Arizona State University

Molecular Reading Head for Single-Molecule DNA Sequencing

$550,000, three years

Andre Marziali, University of British Columbia

Nanopores for Trans-Membrane Bio-Molecule Detection

$650,000, three years

J. Michael Ramsey, University of North Carolina

Nanotechnology for the Structural Interrogation of DNA

$2 million, two years


The Scan

Study Finds Few FDA Post-Market Regulatory Actions Backed by Research, Public Assessments

A Yale University-led team examines in The BMJ safety signals from the US FDA Adverse Event Reporting System and whether they led to regulatory action.

Duke University Team Develops Programmable RNA Tool for Cell Editing

Researchers have developed an RNA-based editing tool that can target specific cells, as they describe in Nature.

Novel Gene Editing Approach for Treating Cystic Fibrosis

Researchers in Science Advances report on their development of a non-nuclease-based gene editing approach they hope to apply to treat cystic fibrosis.

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.