NEW YORK, May 22 – Senomyx said Tuesday that it had appointed Paul Grayson chairman of the board and promoted Mark Zoller to the position of chief scientific officer, continuing a management reshuffle that has taken place over the past month.

Grayson, who is CEO of the company, and Zoller, who is vice president of research, will be replacing Lubert Stryer in his roles as chairman and CSO.

Stryer is returning to Stanford University following a two-year sabbatical at Senomyx.