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Scientists in Sweden Sequence Trench Fever, Carrin s Disease Pathogens

NEW YORK, June 25 (GenomeWeb News) -- Scientists at Uppsala University in Sweden have sequenced and compared the genomes of two human pathogens transmitted by lice, Bartonella quintana and Bartonella henselae.

 

The results were published online ahead of print this week in PNAS.

 

B. quintana causes trench fever, a disease that affected more than one million soldiers during World War I, and is transmitted by the human body louse. B. henselae infects both humans, where it causes Carrión's disease, and cats, which do not show symptoms.

 

Both genomes are very similar, but B. quintana's genome, at 1.6 Mb, is smaller than B. henselae's, at 1.9 Mb. Moreover, B. henselae possesses genomic islands coding for filamentous hemagglutinin.

 

Click here for the abstract of the study.

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