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Scientists in Sweden Sequence Trench Fever, Carrin s Disease Pathogens

NEW YORK, June 25 (GenomeWeb News) -- Scientists at Uppsala University in Sweden have sequenced and compared the genomes of two human pathogens transmitted by lice, Bartonella quintana and Bartonella henselae.

 

The results were published online ahead of print this week in PNAS.

 

B. quintana causes trench fever, a disease that affected more than one million soldiers during World War I, and is transmitted by the human body louse. B. henselae infects both humans, where it causes Carrión's disease, and cats, which do not show symptoms.

 

Both genomes are very similar, but B. quintana's genome, at 1.6 Mb, is smaller than B. henselae's, at 1.9 Mb. Moreover, B. henselae possesses genomic islands coding for filamentous hemagglutinin.

 

Click here for the abstract of the study.

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.