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Scientists Sequence Genome of Horse Pathogen

NEW YORK, Sept. 21 (GenomeWeb News) - Scientists led by the Institute for Genomic Research have sequenced the genome of Burkholderia mallei, a pathogen that causes the horse disease glanders and has been used as a biological weapon in several wars.

 

The study, published online last week in PNAS, found that B. mallei, which infects mainly horses, mules, and donkeys but also humans, has a highly regulated set of virulence genes and an unstable genome.

 

TIGR said it is now examining several other strains and isolates of B. mallei as well as B. pseudomallei under an NIAID microbial sequencing contract.

The Scan

Shape of Them All

According to BBC News, researchers have developed a protein structure database that includes much of the human proteome.

For Flu and More

The Wall Street Journal reports that several vaccine developers are working on mRNA-based vaccines for influenza.

To Boost Women

China's Ministry of Science and Technology aims to boost the number of female researchers through a new policy, reports the South China Morning Post.

Science Papers Describe Approach to Predict Chemotherapeutic Response, Role of Transcriptional Noise

In Science this week: neural network to predict chemotherapeutic response in cancer patients, and more.