You can't get much better resolution than the single-nucleotide level. Joe Ecker and his team at the Salk Institute report that they've done just that to look at the epigenome of Arabidopsis thaliana. "Our aim was to really go much further — previously, genome-wide analysis of genome methylation of Arabidopsis had used tiling microarrays — and really go to the ultimate resolution of DNA methylation," says Ryan Lister, a postdoc in Ecker's lab and first author on the Cell paper describing their work.

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Cancer researcher Alan Rabson has died at 92, the New York Times reports.

As the National Guideline Clearinghouse goes dark, the ECRI Institute says it will pick up the slack.

In Genome Research this week: sequencing method examines proteins parasite uses to evade immune system, L1 insertions in cancer, and more.

The Atlantic reports on private Facebook support groups for people who receive unexpected parentage results from direct-to-consumer genetic tests.