Skip to main content
Premium Trial:

Request an Annual Quote

SAEC Releases Genetic Data Related to Drug-Induced Liver Injury, Serious Skin Reactions

Premium

By Turna Ray

The International Serious Adverse Events Consortium this week released genetic data on drug-induced liver injury and serious skin reactions, its third data release since the public-private collaboration launched three years ago.

SAEC is a non-profit consortium formed in October 2007 between industry, academia, the Wellcome Trust, and the US Food and Drug Administration to identify genetic variants associated with serious adverse events [see PGx Reporter 06-03-2009].

The new data, relating to 368 cases of drug-induced liver injury and 15 cases of serious skin reactions, expand on data that SAEC released in December 2008 and May 2009.

“FDA is pleased with the Consortium's progress,” ShaAvhree Buckman, director of the Office of Translational Sciences in the FDA’s Center for Drug Evaluation and Research, said in a statement announcing the data release. “The continued accumulation of scientific information on the genetic basis of adverse drug events provides researchers with invaluable tools for understanding why some people respond to medicines differently than others."

Researchers who enter into a data use agreement with the SAEC can obtain free access to the newly released data from the non-profit's website, generate custom data inquiries, and receive immediate results.

The Scan

Just Breathing

A new analysis suggests that most Mycobacterium tuberculosis is spread by aerosols from breathing, rather than by coughing, the New York Times reports.

Just Like This One

NPR reports that the World Health Organization has hired a South African biotech company to recreate mRNA vaccine for SARS-CoV-2 that is similar to the one developed by Moderna.

Slow Start

The Wall Street Journal reports that Biogen's Alzheimer's disease treatment had revenues for July through September that totaled $300,000.

Genome Research Papers on Cancer Chromatin, Splicing in the Thymus, Circular RNAs in Cancer

In Genome Research this week: analysis of bivalent chromatin sites, RBFOX splicing factors' role in thymic epithelial cells, and more.