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Rubicon Licenses DNA Amplification Tech to Sigma-Aldrich

NEW YORK, Oct. 5 (GenomeWeb News) - Rubicon Genomics has granted Sigma-Aldrich an exclusive, worldwide license to GenomePlex, Rubicon's whole-genome amplification technology, the companies said today.


Under the terms of the agreement, Sigma-Aldrich will have exclusive world-wide rights to produce and sell GenomePlex kits to the research market. Rubicon, based in Ann Arbor, Mich., will retain all rights to the technology for its core market - molecular diagnostics - as well as for service, the companies said.


Financial details of the agreement were not disclosed.


Rubicon said that GenomePlex amplifies total human DNA at the sub-nanogram level by using random, non-enzymatic fragmentation of genomic DNA followed by the addition of specific adaptor sequences to both ends, forming an in vitro molecular library that can be amplified with conventional techniques.

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