Skip to main content
Premium Trial:

Request an Annual Quote

Rosetta Genomics, NYU Add Neonatal Heart Disorder to miRNA Cancer Alliance

NEW YORK (GenomeWeb News) — Rosetta Genomics has added congenital neonatal cardiovascular disease to a collaboration with the New York University School of Medicine that was originally created to use miRNA technology to develop cancer diagnostics, the company said today.
Rehovot, Israel-based Rosetta Genomics said the research will screen for specific miRNA biomarkers and signatures that could help diagnose or target congenital heart disease in newborns.
Around 40,000, or one out of every 125, US infants are born with CHD, which is caused by the improper development of vessels near the heart, the company said.
"It is now clear that microRNAs play a key role in controlling diverse aspects of cardiac development and response to disease," David Meyer, director of the Pediatric and Congenital Cardiothoracic Surgery at NYU, said in a statement.
“Recent studies have revealed key roles of microRNAs as regulators of growth, development, function, and responses to stress in the heart,” Rosetta Genomics said, adding that these “regulatory mechanisms may serve as potential diagnostic biomarkers and therapeutic targets for the treatment of heart disease.”
Financial terms of the expanded agreement were not released.
The Scan

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.

Family Genetic Risk Score Linked to Diagnostic Trajectory in Psychiatric Disorders

Researchers in JAMA Psychiatry find ties between high or low family genetic risk scores and diagnostic stability or change in four major psychiatric disorders over time.

Study Questions Existence of Fetal Microbiome

A study appearing in Nature this week suggests that the reported fetal microbiome might be the result of sample contamination.

Fruit Fly Study Explores Gut Microbiome Effects on Circadian Rhythm

With gut microbiome and gene expression experiments, researchers in PNAS see signs that the microbiome contributes to circadian rhythm synchronicity and stability in fruit flies.