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Roche Taps Compugen to Seek Non-SNP Markers for Drug Response

NEW YORK (GenomeWeb News) – Compugen and Roche have agreed to collaborate in an effort to search for biomarkers that could help predict patient responses to drugs aimed at treating rheumatoid arthritis, Compugen said Thursday.
 
Compugen will use its GeneVa database, which holds around 200,000 non-SNP genetic variations, to investigate DNA samples for markers that could predict response or non-response to selected drugs Roche intends to develop.
 
GeneVa includes algorithms and other computational biology tools to find variations that are associated with specific phenotypes that may be linked to particular drug responses.
 
Financial terms of the agreement were not released.

The Scan

Two J&J Doses

Johnson & Johnson says two doses of its SARS-CoV-2 vaccine provides increased protection against symptomatic COVID-19, CNN reports.

Pfizer-BioNTech Vaccine Response in Kids

The Pfizer-BioNTech SARS-CoV-2 vaccine in a lower-dose format appears to generate an immune response among children, according to the Washington Post.

Chicken Changes to Prevent Disease

The Guardian writes that researchers are looking at gene editing chickens to help prevent future pandemics.

PNAS Papers on Siberian Dog Ancestry, Insect Reproduction, Hippocampal Neurogenesis

In PNAS this week: ancestry and admixture among Siberian dogs, hormone role in fruit fly reproduction, and more.