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Roche R&D Group To Use Genedata's Refiner MS Module

NEW YORK (GenomeWeb News) - Genedata said last week that Roche Molecular Medicine Laboratories in Basel, Switzerland, will integrate its Expressionist Refiner MS module within its proteomics analysis pipeline.

Refiner MS automatically assesses and pre-processes mass spectrometry-based proteomics and metabolomics data.
Genedata CEO Othmar Pfannes told GenomeWeb Daily News sister publication BioInform that the agreement builds on a collaboration that the companies began several years ago to validate the throughput of Refiner MS.
He said that the software is designed to handle MS data from clinical studies involving several thousand patients, and that Roche is one of several customers that validated the software in smaller studies involving 30 to 40 patients.
Pfannes said that pre-processing of MS data is particularly important for large-scale proteomics and metabolomics studies because the mis-identification of just a single peak “could lead to a lot of wrong comparisons.”
He said that a number of Genedata’s customers are moving toward using mass spec in large-scale clinical studies, and noted that “It looks like this is going to be a major success for us over the next six months or so.”

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.