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Researchers Sequence Genome of Probiotic Bacterium L. Acidophilus

NEW YORK, Jan. 20 (GenomeWeb News) - Scientists from the Southeast Dairy Foods Research Center at NC State, Danisco, and the California Polytechnic State University have sequenced the genome of Lactobacillus acidophilus NCFM.


L. acidophilus NCFM is a lactic acid bacterium that lives in the upper intestinal tract of humans and animals and has been commercially produced since 1972. It is considered to have probiotic properties, offering a number of health benefits.


The genome, published in this week's online edition of PNAS, consists of nearly 2 million base pairs with almost 2,000 predicted open reading frames.


The researchers found several features in the sequence that they believe enable the bacterium to survive in the gastrointestinal tract and interact with the intestinal mucosa and microbiota.

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