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Researchers Sequence Dehalococcoides Strain CBDB1, Bacteria That Break Down Chlorinated Organic Pollutants

NEW YORK, Aug. 22 (GenomeWeb News) - A team of researchers from Germanyand the UShas sequenced the genome of Dehalococcoides sp. strain CBDB1, anaerobic bacteria that break down many of the most toxic and persistent chlorinated organic chemicals.


The microbe's 1,395,502 base pair genome contains 32 reductive-dehalogenase-homologous genes, possibly giving it its immense dehalogenating potential. A comparison with the recently sequenced genome of Dehalococcoides ethenogenes strain 195 revealed a high degree of gene context conservation but also high plasticity in regions containing rdh genes.


The scientists, from the Max-Planck-Institute of Molecular Genetics in Berlin, Technical UniversityBerlin, and CornellUniversity, published their study yesterday online in Nature Biotechnology.

The Scan

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.