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Recent Molecular Biology Tool Patents Issued in the US to BCW Index Companies: Jul 21, 2005

Company US
Patent No.
Date Issued Title
Agilent Technologies
6,919,531
July 19 Methods for producing glass substrates for use in biopolymeric microarrays
6,919,181
July 19 Methods for generating ligand arrays
6,916,633
July 12 Method for linear mRNA amplification
6,914,242
July 5 Time of flight ion trap tandem mass spectrometer system
6,914,229
July 5 Signal offset for prevention of data clipping in a molecular array scanner
6,909,970
June 21 Fast microarray expression data analysis method for network exploration
Applera
6,919,445
July 19 Methods of labelling polynucleotides with dibenzorhodamine dyes
6,916,447
July 12 Apparatus and method for transferring small volumes of substances
6,913,897
July 5 Kit for conducting an assay to detect a substance using enzymatically-induced decomposition of dioxetanes
6,909,974
June 21 System and method for discovery of biological instruments
6,905,826
June 14 Methods and compositions for microarray control
Beckman Coulter
6,919,044
July 19 Sample loading and handling interface to multiple chemistry analyzers
6,908,226
June 21 Method and apparatus for aspirating liquid from a container
Bruker Daltonics
6,906,324
June 14 Apparatus and method for analyzing samples in a dual ion trap mass spectrometer
Invitrogen and Sloan-Kettering Institute for Cancer Research
6,916,632
July 12 Methods and reagents for molecular cloning
Invitrogen
6,916,423
July 12 Device and methods for subdividing and filtering gel material and extracting molecules therefrom
6,905,858
June 14 Nucleic acid-free thermostable enzymes and methods of production
Sigma-Aldrich
6,902,914
June 7 Recombinant DNA processes using a dNTP mixture containing modified nucleotides
The Scan

Expanded Genetic Testing Uncovers Hereditary Cancer Risk in Significant Subset of Cancer Patients

In Genome Medicine, researchers found pathogenic or likely pathogenic hereditary cancer risk variants in close to 17 percent of the 17,523 patients profiled with expanded germline genetic testing.

Mitochondrial Replacement Therapy Embryos Appear Largely Normal in Single-Cell 'Omics Analyses

Embryos produced with spindle transfer-based mitochondrial replacement had delayed demethylation, but typical aneuploidy and transcriptome features in a PLOS Biology study.

Cancer Patients Report Quality of Life Benefits for Immune Checkpoint Inhibitors

Immune checkpoint inhibitor immunotherapy was linked in JAMA Network Open to enhanced quality of life compared to other treatment types in cancer patients.

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.