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Reaction Biology Wins $750K SBIR Grant to Apply Array Tech to Drug Discovery

NEW YORK, Aug. 9 (GenomeWeb News) - Reaction Biology has been awarded a $750,000 Phase II SBIR grant from the National Institutes of Health to apply its new DiscoveryDot microarray technology for drug discovery, the company said today.    


The grant, from the National Institute of Dental and Craniofacial Research, will fund the use of the technology for high throughput screening of caspases and other proteases, Reaction Biology said.


The company said its DiscoveryDot technology can screen up to 6,600 individual reactions. The one-nanoliter reaction volume used by the company "represents 1/10,000 the volume of conventional screening systems," Reaction Biology said.

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.