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Quantum Dot Nabs Trio of Patents for HTP Genotyping Technology

NEW YORK, Sept. 4 (GenomeWeb News) - Quantum Dot has secured three additional patents for its QDOT high-throughput genotyping technology, the company said today.


QDC will retain exclusive, worldwide license for biological applications for all three patents, which the firm licensed from the Massachusetts Institute of Technology.

The first patent, US Patent No. 6,576,291, enables the large-scale production of Quantum Dot's highly luminescent semiconductor nanocrystals, which Quantum Dot said is key in preparing its QDOT products. The patented technology employs metal salt precursors that may be used on an open bench with "a minimal risk of hazard," Quantum Dot said. Earlier methods for preparing quantum dots required "dangerous" organometallic precursor materials that needed to be used in an inert, dry environment, Quantum Dot said.


Moungi Bawendi and Nathan Stott of MIT are the inventors. Bawendi is a consultant to Quantum Dot and serves on the company's scientific advisory board.


The second patent, US Patent No. 6,602,932, is entitled "Semiconductor Nanocrystals for Inventory Control" and is for technology that encompasses populations of SCNCs that have "distinct characteristic spectral emissions" linked to a solid support, such as a bead, according to Quantum Dot. The spectral emissions can be a wavelength of emitted light, an intensity of emitted light, or both, the company explained.


Bawendi and Klavs Jensen, also of MIT, are the inventors.


The third patent, US Patent No. 6,607,829, is entitled "Tellurium-containing Nanocrystalline Materials" and covers nanocrystallite materials that can emit in the near infrared region of the light spectrum. These ranges of emission are "particularly useful" for in vivo research, Quantum Dot said.


Bawendi, Frederic Mikulec, and Sungjee Kim of MIT are the inventors.


Quantum Dot's QDOTs illuminate like molecular-scale LEDs and enable researchers to perform genotyping experiments and highly sensitive measurements of drug efficacy at the cellular level, the company said.

Recently, Japanese consumer-electronics giant Matsushita Electric Industrial -- which owns brands like Panasonic and Quasar -- agreed to develop and manufacture a high-throughout SNP-genotyping platform based on the QDOT technology


The arrangement will enable Quantum Dot to begin marketing its Qbead technology to its two development partners in early fall, a Quantum Dot official said recently.

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