Skip to main content
Premium Trial:

Request an Annual Quote

Qiagen Partners with U Penn Team to Identify Molecular Signatures for Gene Doping

NEW YORK (GenomeWeb News) – Qiagen said today that it is partnering with researchers from the University of Pennsylvania to develop molecular tests to detect gene doping in athletes.
In the project, supported by the World Anti-Doping Agency and Qiagen, the U Penn team plans to climb Mount Everest with live mice. The researchers plan to use tissue and blood samples from these mice to identify a molecular signature for altitude-induced hypoxia, or oxygen deficiency.
Hypoxia stimulates the creation of erythropoietin, which promotes the production of red blood cells and is a commonly abused doping agent. While current tests fo doping can detect artificial EPO, it is very difficult to determine whether athletes have used genetic manipulation to produce more natural EPO, Qiagen said.  
The company said that the scientists plan to develop new tests for gene doping by comparing the “natural” molecular signatures obtained from the mice exposed to high altitudes with “induced” signatures created by gene doping.
"From a research point of view, a major challenge of this endeavor will be the extraction of samples from the mice under these extreme conditions," said Gabriel Willmann, an investigator on the project, in a statement. He said that the team will use Qiagen’s tools to collect, process, and analyze the samples.

The Scan

More Boosters for US

Following US Food and Drug Administration authorization, the Centers for Disease Control and Prevention has endorsed booster doses of the Moderna and Johnson & Johnson SARS-CoV-2 vaccines, the Washington Post writes.

From a Pig

A genetically modified pig kidney was transplanted into a human without triggering an immune response, Reuters reports.

For Privacy's Sake

Wired reports that more US states are passing genetic privacy laws.

Science Paper on How Poaching Drove Evolution in African Elephants

In Science this week: poaching has led to the rapid evolution of tuskless African elephants.