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Pyrosequencing Pins Pair of Patents for Pyrophosphate Detection

NEW YORK, Aug. 28 – Pyrosequencing has won a pair of patents from the US government for its genetic analysis technology, the company said on Tuesday.

According to Uppsala, Sweden-based Pyrosequencing, both patents cover DNA sequencing based on real-time pyrophosphate detection. The first patent, 6,210,891, deals with methods for sequencing DNA “where the incorporated bases [are] coupled to the release of pyrophosphate and its detection via a light signal,” the company said in a statement.

The second patent, 6,258,568, covers the detection of “pyrophosphate release as new nucleotides are added to a growing DNA strand and then degrading the unincorporated nucleotides. …”

In May, Pyrosequencing, which develops, manufactures and sells DNA sequencing systems for applied genetic analysis, came one step closer to entering the diagnostic market after it won a patent for assessing cardiovascular conditions such as myocardial infarction.

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