In Pursuit of a Great Idea

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His are some of the giant shoulders upon which genomics will forever stand. Some of the concepts Aravinda Chakravarti developed while working alongside Francis Collins and others to map and clone the CFTR gene in the 1980s are still in use today. "Twenty years later we're using the same damn [approach], we now have companies, we make millions of markers, we have fancy computer programs," says Chakravarti, currently a professor of medicine, pediatrics, and molecular biology and genetics at the Johns Hopkins University School of Medicine.

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